产品说明
一般描述
Cyclobenzaprine is a tricyclic agent, which has anti-depressant and anti-cholinergic properties. It lowers the tonic somatic motor activity of motor neuron systems. Cyclobenzaprine prevents the uptake of noradrenaline. It is used to treat neck, back and myofascial pain. Cyclobenzaprine functions as a nerve impulse inhibitor.
应用
Cyclobenzaprine hydrochloride has been used to study its effects on the muscles of dystrophin-deficient mdx5Cv mice.
Cyclobenzaprine hydrochloride has been used to study its effect on the muscles of dystrophin-deficient mdx5Cv mice.
生化/生理作用
Skeletal muscle relaxant; reduces muscle spasm by depression of brainstem neurons; 5-HT2 serotonin receptor antagonist.
Cyclobenzaprine hydrochloride is a type of tricyclic skeletal drug, which is commonly used as a muscle relaxant. It is very effective in treating intractable pain of cervical and lumbar origin caused by skeletal muscle spasm. cyclobenzaprine hydrochloride inhibit tonic α-mononeuronal excitation mediated by descending serotonergic systems by interacting with serotonin receptors at the spinal cord level.
特点和优势
This compound was developed by Johnson & Johnson. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
基本信息
| 经验(实验)分子式 | C20H21N · HCl |
| 分子量 | 311.85 |
| EC 号 | 228-264-4 |
| MDL编号 | MFCD00079039 |
| PubChem化学物质编号 | 24278315 |
| NACRES | NA.77 |
产品性质
| 质量水平 | 200 |
| 创始人 | Johnson & Johnson |
| SMILES string | Cl.CN(C)CC\C=C1\c2ccccc2C=Cc3ccccc13 |
| InChI | 1S/C20H21N.ClH/c1-21(2)15-7-12-20-18-10-5-3-8-16(18)13-14-17-9-4-6-11-19(17)20;/h3-6,8-14H,7,15H2,1-2H3;1H |
| InChI key | VXEAYBOGHINOKW-UHFFFAOYSA-N |
| Gene Information | human ... HTR2A(3356), HTR2B(3357), HTR2C(3358) |
安全信息
| 象形图 |  |
| 警示用语： | Danger |
| 危险声明 | H301 - H312 + H332 |
| 预防措施声明 | P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P312 |
| 危险分类 | Acute Tox. 3 Oral - Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation |
| 储存分类代码 | 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
