产品说明
一般描述
Cholecalciferol, also called vitamin D3, promotes the absorption of calcium and phosphorus in the body to regulate bone growth. It is most commonly found in humans and animals and is produced in our skin when exposed to sunlight. It is used to treat and prevent bone disorders (such as rickets, osteomalacia).
应用
Cholecalciferol has been used as an internal standard in high-performance liquid chromatography (HPLC) to analyze serum vitamin D levels. It has also been used as a standard in liquid chromatography-electrospray ionization tandem mass spectrometry (LC-ESI-MS/MS) to quantify vitamin D
Cholecalciferol may be used as an analytical reference standard for the determination of the analyte in pharmaceutical formulations by liquid chromatography.
包装
1, 5 amp in ampule
Packaged in flame-sealed ampules under Argon
生化/生理作用
维生素 D 借以发挥作用的受体是配体依赖性转录因子超家族的成员。调控正常细胞和癌细胞的增殖和分化。对乳腺癌、结肠癌和前列腺癌细胞具有抗增殖和抗转移作用。肠和骨骼中的活化维生素 D 受体维持着钙的吸收和平衡。
Cholecalciferol is sourced either through the diet or exposing skin to ultraviolet rays. Oral administration of vitamin D
基本信息
| 经验(实验)分子式 | C27H44O |
| 分子量 | 384.64 |
| Beilstein | 2339331 |
| EC 号 | 200-673-2 |
| MDL编号 | MFCD00078131 |
| eCl@ss | 34058003 |
| PubChem化学物质编号 | 24893197 |
| NACRES | NA.77 |
产品性质
| 质量水平 | 200 |
| 生物来源 | synthetic (organic - wool) |
| 等级 | analytical standard |
| 测定 | ≥97.0% |
| 形式 | crystalline |
| 包装 | pkg of 250 mg |
| 颜色 | white |
| mp | 83-86 ℃ (lit.) |
| 储存温度 | 2-8℃ |
| SMILES string | CC(C)CCC[C@@H](C)[C@@]1([H])CC[C@@]([C@]1(C)CCC/2)([H])C2=C\C=C(C[C@@H](O)CC3)/C3=C |
| InChI | 1S/C27H44O/c1-19(2)8-6-9-21(4)25-15-16-26-22(10-7-17-27(25,26)5)12-13-23-18-24(28)14-11-20(23)3/h12-13,19,21,24-26,28H,3,6-11,14-18H2,1-2,4-5H3/b22-12+,23-13-/t21-,24+,25-,26+,27-/m1/s1 |
| InChI key | QYSXJUFSXHHAJI-YRZJJWOYSA-N |
| Gene Information | human ... VDR(7421) |
安全信息
| 象形图 |   |
| 警示用语： | Danger |
| 危险声明 | H300 + H310 + H330 - H372 |
| 预防措施声明 | P260 - P262 - P280 - P302 + P352 + P310 - P304 + P340 + P310 - P314 |
| 危险分类 | Acute Tox. 2 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - STOT RE 1 Oral |
| 储存分类代码 | 6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials |
| WGK | WGK 2 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | Eyeshields, Faceshields, Gloves, type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
