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DMT-2′O-TC-rG(ib) Phosphoramidite

N2-Isobutyryl-O5′-(4,4′-dimethoxytrityl)-O2′-(1,1-dioxothiomorpholine-4-thiocarbonyl)guanosine O3′-(O-(2-cyanoethyl)-N,N-diisopropylphosphoramidite)

品牌
Sigma-Aldrich
CAS
1219089-77-6
货号
G211630
规格纯度
configured for ABI
参考价格
8513.19 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

法律信息

For use with Customer Container sold to end user customers either directly or through distributors.
This product is manufactured and sold under a license from Agilent Technologies under under US Patent No. 8,202,983 and pending U.S. Patent App. Nos. 13/485,5925, 13/531,191, and 13/339,082 and corresponding foreign counterparts, including those issuing from PCT/US08/63342 and PCT/US09/057922 all assigned to Agilent Technologies. The purchase of this product conveys to the buyer the limited, non-exclusive, non-transferable right (without the right to resell, repackage, or further sublicense) under these patents to use the product to synthesize Oligonucleotides for buyer′s internal research use only, including commercial purposes. Except as otherwise provided herein, no other license is granted to the buyer weather expressly, by implication, by estoppel or otherwise. Buyer agrees and understands that it is not licensed to use this product to synthesize Oligonucleotides for sale, for diagnostic uses including use in clinical diagnostic settings where the use in conjunction with an individual′s sample generates data provided to an individual or the individual′s caregiver for a free reimbursement, neither can Oligonucleotides synthesized using this product be used for use clinical trials or for other therapeutic purposes. This product is sold pursuant to authorization from Agilent Technologies, Inc. and Agilent Technologies reserves all other rights under these patents.
For use with all sales where the purchaser is required to have its own direct license from Agilent, without limitation, Bulk Quantity Sales, and sales to Oligo Houses.
This product and it uses are covered by under US Patent No. 8,202,983 and pending U.S. Patent App. Nos. 13/485,5925, 13/531,191, and 13/339,082 and corresponding foreign counterparts, including those issuing from PCT/US08/63342 and PCT/US09/057922 all assigned to Agilent Technologies. This product is sold to purchaser pursuant to authorization by Agilent Technologies, Inc. without any rights conferred by seller, based on purchaser′s direct license and authorization to purchase from Agilent Technologies, Inc. No license is granted to the purchaser weather expressly, by implication, by estoppel or otherwise on account of this purchase. Purchase′s rights to use this product are governed solely and expressly by purchaser′s direct license agreement with Agilent.

基本信息

经验(实验)分子式C49H61N8O11PS2
分子量1033.16
MDL编号MFCD19105659
PubChem化学物质编号329799877

产品性质

产品线Proligo Reagents
质量水平200
测定≥98% (31P-NMR)
≥98.0% (reversed phase HPLC)
形式solid
technique(s)oligo synthesis: suitable
杂质≤0.3 wt. % water content (Karl Fischer)
≤0.5% 3′-TC isomer (reversed phase HPLC)
≤0.5% P(III) Impurities 145-155ppm (31P-NMR)
颜色 white to light yellow
溶解性acetonitrile: toluene (1:1): 0.1 M at 18 ℃, clear
λconforms (UV/VIS Identity)
相容性configured for ABI
核苷分析base: guanosine
base protecting group: isobutyryl
2' protecting group: TC
5' protecting group: DMT
deprotection: fast
储存温度−20℃
SMILES stringCOc1ccc(cc1)C(OC[C@H]2O[C@H]([C@H](OC(=S)N3CCS(=O)(=O)CC3)[C@@H]2OP(OCCC#N)N(C(C)C)C(C)C)n4cnc5C(=O)NC(NC(=O)C(C)C)=Nc45)(c6ccccc6)c7ccc(OC)cc7
InChI1S/C49H61N8O11PS2/c1-31(2)44(58)53-47-52-43-40(45(59)54-47)51-30-56(43)46-42(67-48(70)55-24-27-71(60,61)28-25-55)41(68-69(65-26-12-23-50)57(32(3)4)33(5)6)39(66-46)29-64-49(34-13-10-9-11-14-34,35-15-19-37(62-7)20-16-35)36-17-21-38(63-8)22-18-36/h9-11,13-22,30-33,39,41-42,46H,12,24-29H2,1-8H3,(H2,52,53,54,58,59)/t39-,41-,42-,46-,69?/m1/s1
InChI keyLXUNLMGCWYNULU-NWGULGMGSA-N

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

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