产品说明
一般描述
α-Cyclodextrin (α-CD) is a cyclic oligosaccharide that consists of six glucopyranose units linked by α-(1,4) bonds. α-CD acts as a soluble dietary fiber and hence it is preferred to be widely used in food industry.
应用
Useful for the solubilization of nonpolar macromolecules such as fatty acids, lipids, and cholesterol for use in cell culture applications. α-Cyclodextrin has been used to solubilize odanacatib, a cathepsin K inhibitor.
包装
1, 5 g in poly bottle
生化/生理作用
α-Cyclodextrin is found to form a firm complex with dietary fats. This way it decreases the bioavailability and absorption of fats. It is known to regulate triglyceride and leptin levels in serum. In rat models, α-Cyclodextrin is shown to induce insulin sensitivity and fecal fat excretion. Thus, α-cyclodextrin is considered to be effective for treating obesity and metabolic syndromes.
基本信息
| 经验(实验)分子式 | C36H60O30 |
| 分子量 | 972.84 |
| Beilstein | 79627 |
| EC 号 | 233-007-4 |
| MDL编号 | MFCD00078207 |
| PubChem化学物质编号 | 24892712 |
| NACRES | NA.77 |
产品性质
| 质量水平 | 200 |
| 无菌性 | non-sterile |
| 产品线 | BioReagent |
| 测定 | ≥98% |
| 形式 | powder |
| technique(s) | cell culture | mammalian: suitable |
| mp | >278 ℃ (dec.) (lit.) |
| 溶解性 | H2O: 10 mg/mL |
| web metadata keyword.default | sigma-aldrich C4680, α-Cyclodextrin powder, BioReagent, suitable for cell culture, Cyclohexaamylose, Cyclomaltohexaose, macromolecule solubilization reagent, fatty acids solubilization reagent, lipid solubilization reagent, cholesterol solubilization reagent. |
| 运输 | ambient |
| 储存温度 | room temp |
| SMILES string | OC[C@H]1O[C@@H]2O[C@H]3[C@H](O)[C@@H](O)[C@H](O[C@@H]3CO)O[C@H]4[C@H](O)[C@@H](O)[C@H](O[C@@H]4CO)O[C@H]5[C@H](O)[C@@H](O)[C@H](O[C@@H]5CO)O[C@H]6[C@H](O)[C@@H](O)[C@H](O[C@@H]6CO)O[C@H]7[C@H](O)[C@@H](O)[C@H](O[C@@H]7CO)O[C@H]1[C@H](O)[C@H]2O |
| InChI | 1S/C36H60O30/c37-1-7-25-13(43)19(49)31(55-7)62-26-8(2-38)57-33(21(51)15(26)45)64-28-10(4-40)59-35(23(53)17(28)47)66-30-12(6-42)60-36(24(54)18(30)48)65-29-11(5-41)58-34(22(52)16(29)46)63-27-9(3-39)56-32(61-25)20(50)14(27)44/h7-54H,1-6H2/t7-,8-,9-,10-,11-,12-,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23-,24-,25-,26-,27-,28-,29-,30-,31-,32-,33-,34-,35-,36-/m1/s1 |
| InChI key | HFHDHCJBZVLPGP-RWMJIURBSA-N |
安全信息
| 象形图 |  |
| 警示用语： | Warning |
| 危险声明 | H319 |
| 预防措施声明 | P305 + P351 + P338 |
| 危险分类 | Eye Irrit. 2 |
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | Eyeshields, Gloves, type N95 (US) |
