产品说明
一般描述
4-Methylpyrazole inhibits CYP2E1 activity. It also acts as alcohol dehydrogenase inhibitor.
应用
Fomepizole (4-Methylpyrazole) can be used as:
- A reactant to prepare 4-methyl-1-phenyl-1H-pyrazole by reacting with bromobenzene via N-arylation using a copper catalyst.
- A starting material for the synthesis of 4-methyl-3(5)-nitropyrazole by nitration.
- A ligand in the preparation of gallium(III) complex of 4-methylpyrazole as potential antitumor and antiviral agent.
甲醇和乙二醇中毒的有效解毒剂。
包装
1, 5 g in glass bottle
生化/生理作用
Alcohol dehydrogenase inhibitor.
醇脱氢酶抑制剂
基本信息
经验(实验)分子式 | C4H6N2 |
分子量 | 82.10 |
Beilstein | 105204 |
EC 号 | 231-445-0 |
MDL编号 | MFCD00005245 |
PubChem化学物质编号 | 24853343 |
NACRES | NA.22 |
产品性质
测定 | 99% |
折射率 | n |
bp | 99-100 ℃/6 mmHg (lit.) |
溶解性 | alcohol: soluble(lit.) water: soluble(lit.) |
密度 | 0.993 g/mL at 25 ℃ (lit.) |
SMILES string | Cc1cn[nH]c1 |
InChI | 1S/C4H6N2/c1-4-2-5-6-3-4/h2-3H,1H3,(H,5,6) |
InChI key | RIKMMFOAQPJVMX-UHFFFAOYSA-N |
Gene Information | human ... ADH1A(124), ADH1B(125), ADH1C(126) |
安全信息
象形图 | |
警示用语: | Warning |
危险声明 | H302 - H315 - H319 - H335 |
预防措施声明 | P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338 |
危险分类 | Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3 |
靶器官 | Respiratory system |
储存分类代码 | 10 - Combustible liquids |
WGK | WGK 3 |
闪点(F) | 204.8 °F - closed cup |
闪点(C) | 96 ℃ - closed cup |
个人防护装备 | Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter |