产品说明
一般描述
Prothionamide is an analogue of ethionamide, and is better tolerated and less toxic than ethionamide. It contains a propyl group instead of an ethyl group at the α position.
Chemical structure: pyridine
包装
1, 10 g in poly bottle
生化/生理作用
Prothionamide is the second line of drug used in leprosy and in tuberculosis. It is highly effective against Mycobacterium tuberculosis. In patients with multidrug-resistant tuberculosis (MDR-TB), prothionamide causes the development of hepatitis. In rare cases, it causes drug reaction with eosinophilia and systemic symptoms (DRESS) in patients with MDR-TB. DRESS is characterized by fever, hematologic abnormalities, skin eruption, and internal organ disruption.
其他说明
Keep container tightly closed in a dry and well-ventilated place. Storage class (TRGS 510): Non Combustible Solids
基本信息
| 经验(实验)分子式 | C9H12N2S |
| 分子量 | 180.27 |
| MDL编号 | MFCD00464119 |
| PubChem化学物质编号 | 329824982 |
| NACRES | NA.85 |
产品性质
| 质量水平 | 200 |
| 测定 | ≥99% (HPLC) |
| 形式 | powder |
| 储存条件 | (Keep container tightly closed in a dry and well-ventilated place. Storage class (TRGS 510) Non Combustible liquids.) |
| 颜色 | yellow |
| 作用机制 | enzyme | interferes |
| 抗生素抗菌谱 | mycobacteria |
| 储存温度 | −20℃ |
| SMILES string | NC(C1=CC(CCC)=NC=C1)=S |
| InChI | 1S/C9H12N2S/c1-2-3-8-6-7(9(10)12)4-5-11-8/h4-6H,2-3H2,1H3,(H2,10,12) |
| InChI key | VRDIULHPQTYCLN-UHFFFAOYSA-N |
安全信息
| 象形图 |  |
| 警示用语： | Warning |
| 危险声明 | H302 |
| 危险分类 | Acute Tox. 4 Oral |
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
