产品介绍：
产品说明
一般描述
Heptakis(2,3,6-tri-O-methyl)-β-cyclodextrin is a β-cyclodextrin derivative that finds potential use in pharmaceutical, food and cosmetic applications. Its attractive features include: the non-polar cavity desirable for its use as a molecular host for a wide range of molecules and its affinity for organic compounds in solution as well as crystalline phases.
应用
Heptakis(2,3,6-tri-O-methyl)-β-cyclodextrin may be used:
- To investigate the crystal structure of its complexes with m-iodophenol, 4-biphenylacetic acid and (R)- and (S)-flurbiprofen by X-ray analysis.
- To study the candidature of its complex with vitamin A for potential application as a drug delivery system for ophthalmic applications by high sensitivity fluorescence spectrometry and high pressure liquid chromatography (HPLC).
- In the determination of analyte composition in commercial samples by HPLC coupled to mass spectrometry (MS).
用于对映体拆分的液相色谱的手性添加剂。通过毛细管电泳对碱性药物的手性分离。
基本信息
| 经验(实验)分子式 | C63H112O35 |
| 分子量 | 1429.54 |
| Beilstein | 78748 |
| MDL编号 | MFCD00010728 |
| PubChem化学物质编号 | 329757734 |
| NACRES | NA.22 |
产品性质
| 质量水平 | 100 |
| 测定 | ≥98.0% (TLC) ≥98.0% |
| 旋光性 | [α]25/D +157±4°, c = 1% in H2O |
| mp | 170-178 ℃ (lit.) |
| 溶解性 | H2O: 50 mg/mL, slightly turbid, colorless |
| 储存温度 | 2-8℃ |
| SMILES string | COC[C@H]1O[C@@H]2O[C@@H]3[C@@H](COC)O[C@H](O[C@@H]4[C@@H](COC)O[C@H](O[C@@H]5[C@@H](COC)O[C@H](O[C@@H]6[C@@H](COC)O[C@H](O[C@@H]7[C@@H](COC)O[C@H](O[C@@H]8[C@@H](COC)O[C@H](O[C@H]1[C@H](OC)[C@H]2OC)[C@H](OC)[C@H]8OC)[C@H](OC)[C@H]7OC)[C@H](OC)[C@H]6OC)[C@H](OC)[C@H]5OC)[C@H](OC)[C@H]4OC)[C@H](OC)[C@H]3OC |
| InChI | 1S/C63H112O35/c1-64-22-29-36-43(71-8)50(78-15)57(85-29)93-37-30(23-65-2)87-59(52(80-17)44(37)72-9)95-39-32(25-67-4)89-61(54(82-19)46(39)74-11)97-41-34(27-69-6)91-63(56(84-21)48(41)76-13)98-42-35(28-70-7)90-62(55(83-20)49(42)77-14)96-40-33(26-68-5)88-60(53(81-18)47(40)75-12)94-38-31(24-66-3)86-58(92-36)51(79-16)45(38)73-10/h29-63H,22-28H2,1-21H3/t29-,30-,31-,32-,33-,34-,35-,36-,37-,38-,39-,40-,41-,42-,43+,44+,45+,46+,47+,48+,49+,50-,51-,52-,53-,54-,55-,56-,57-,58-,59-,60-,61-,62-,63-/m1/s1 |
| InChI key | DSDAICPXUXPBCC-MWDJDSKUSA-N |
安全信息
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | Eyeshields, Gloves, type N95 (US) |
