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Fmoc-(R)-2-(7-octenyl)Ala-OH

品牌
Sigma-Aldrich
CAS
945212-26-0
货号
F6562
包装型号
规格纯度
参考价格
1990.81 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

应用

Olefinic alpha-methyl amino acid for peptide stapling. Upon incorporation of this amino acid into a peptide, along with another of the same or derivative with a different length of the olefinic side chain, the two can be ′stapled′ via a ring closing metathesis reaction with Grubb′s catalyst (product # 579726). The resulting stapled peptide macrocycle has been shown to stabilize the alpha-helical structure of peptides, which can lead to favorable biological characteristics such as increased proteolytic stability and cellular uptake.

包装

1, 5 g in glass bottle

基本信息

经验(实验)分子式C26H31NO4
分子量421.53
MDL编号MFCD12925761
PubChem化学物质编号329799756
NACRESNA.26

产品性质

质量水平200
形式solid
reaction suitabilityreaction type: Fmoc solid-phase peptide synthesis
application(s)peptide synthesis
官能团Fmoc
储存温度−20℃
SMILES stringO=C(OCC1C(C=CC=C2)=C2C3=C1C=CC=C3)N[C@@](CCCCCCC=C)(C)C(O)=O
InChI1S/C26H31NO4/c1-3-4-5-6-7-12-17-26(2,24(28)29)27-25(30)31-18-23-21-15-10-8-13-19(21)20-14-9-11-16-22(20)23/h3,8-11,13-16,23H,1,4-7,12,17-18H2,2H3,(H,27,30)(H,28,29)/t26-/m1/s1
InChI keyMADFVGMQNXRFAF-AREMUKBSSA-N

安全信息

象形图GHS09
警示用语:Warning
危险声明H400
预防措施声明P273
危险分类Aquatic Acute 1
储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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