产品说明
一般描述
DSPE-PEG(2000) Folate, also known as 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[folate(polyethylene glycol)-2000], is a functionalized PEG lipid. This lipid is added into liposomes as a targeting ligand for folate receptors, which acts as cellular surface markers for numerous solid tumors and myeloid leukemias. Folate targeted drug delivery is used an effective therapy for the treatment and imaging of various cancers and inflammatory diseases. Folate conjugates with low molecular weight and high binding affinity for folate receptors (FR) on cell surface deliver a variety of molecular complexes such as protein toxins, immune stimulants, chemotherapeutic agents, liposomes, nanoparticles, and imaging agents to pathologic cells without affecting normal tissues.
应用
DSPE-PEG(2000) Folate(1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[folate(polyethylene glycol)-2000]) may be used in preparation of folate-conjugated liposomes and folate-modified microvesicles (MVs).
包装
5 mL Clear Glass Sealed Ampule (880124X-10mg)
5 mL Clear Glass Sealed Ampule (880124X-1mg)
基本信息
| NACRES | NA.25 |
产品性质
| 包装 | pkg of 1 × 1 mL (880124X-10mg) pkg of 1 × 1 mL (880124X-1mg) |
| manufacturer/tradename | Avanti Polar Lipids 880124X |
| 浓度 | 1 mg/mL (880124X-1mg) 10 mg/mL (880124X-10mg) |
| 运输 | dry ice |
| 储存温度 | −20℃ |
安全信息
| 象形图 |    |
| 警示用语： | Danger |
| 危险声明 | H226 - H302 - H315 - H319 - H331 - H336 - H351 - H361d - H371 - H372 |
| 预防措施声明 | P201 - P210 - P301 + P312 + P330 - P302 + P352 - P304 + P340 + P311 - P308 + P311 |
| 危险分类 | Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Flam. Liq. 3 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 2 - STOT SE 3 |
| 靶器官 | Central nervous system, Eyes |
| 储存分类代码 | 3 - Flammable liquids |
| WGK | WGK 3 |
| 闪点(F) | 80.6 °F |
| 闪点(C) | 27 ℃ |
