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CyreneTM 2-Methyltetrahydrofuran Blend

品牌
Sigma-Aldrich
货号
920193
规格纯度
BioRenewable
参考价格
1341.65 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Cyrene 2-Methyltetrahydrofuran Blend with BHT as an inhibitor is specially formulated for use in automated processes and applications where lower viscosity is required, making it easier to handle while maintaining high yields.
This Cyrene blend is an alternative for NMP and DMF in many cross-coupling reactions. Neither Cyrene nor 2-Methyltetrahydrofuran have any genotoxic or mutagenic concerns associated with their use, making them much safer alternatives to traditional aprotic solvents.
This new blend is part of our Biorenewable product line, meaning that it is made from renewable resources and does not compete with food resources for its production, making it more environmentally sustainable for the future. The material has also been independently certified as 100% renewable carbon.

应用

This cosolvent solution has been shown to have similar reaction yields to NMP and DMF for many cross-coupling reactions, such as:

  • HATU Amide Coupling - Replacement for DMF in amide and dipeptide coupling reactions (eq. 1)
  • Suzuki-Miyaura coupling reaction (eq. 2)
  • Sonogashira coupling reaction (eq. 3)

特点和优势

  • Independently certified as 100% renewable carbon.
  • Closer physical properties of NMP and DMF while maintaining high reaction yields.
  • Sustainably produced and environmentally less hazardous than more traditional petroleum aprotic solvents
  • Both Cyrene and 2-MeTHF are also much safer for handling without the genotoxic concerns of other solvents.
  • It has a lower viscosity than neat Cyrene making it more optimized for automated processes. (See Table 2)

其他说明

To see other BioRenewable or Greener Solvents

法律信息

CYRENE is a trademark of Circa Group Pvt Ltd

基本信息

经验(实验)分子式C6H8O3
分子量128.13

产品性质

形式liquid
包含30-80 ppm BHT as stabilizer
环保替代产品特性Safer Solvents and Auxiliaries
Use of Renewable Feedstocks
Learn more about the Principles of Green Chemistry.
密度1.153 g/mL
环保替代产品分类Aligned

安全信息

象形图GHS02GHS05
警示用语:Danger
危险声明H225 - H315 - H318
预防措施声明P210 - P233 - P240 - P280 - P303 + P361 + P353 - P305 + P351 + P338
危险分类Eye Dam. 1 - Flam. Liq. 2 - Skin Irrit. 2
补充剂危害EUH019
储存分类代码3 - Flammable liquids
WGKWGK 2

Sigma-Aldrich

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