产品说明
一般描述
Chemical structure: quinolone
应用
Cinoxacin was used to study the rat renal organic anion transporter 1 (OAT1). It is used to study fluoroquinolone-resistant Streptococcus pyogenes.
生化/生理作用
Cinoxacin is a synthetic antimicrobial agent that interferes with DNA replication by inhibiting DNA gyrase and topoisomerase IV (topo IV) through tight DNA binding. The mechanism of action of cinoxacin is comparable to nalidixic acid. Cinoxacin is effective against Gram-negative bacteria and is often used to treat urinary tract infections caused by E. coli, Proteus mirabilis, Proteus vulgaris and Klebsiella sp.
其他说明
Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. C8645.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.
Keep container tightly closed in a dry and well-ventilated place.
基本信息
| 经验(实验)分子式 | C12H10N2O5 |
| 分子量 | 262.22 |
| EC 号 | 249-133-8 |
| MDL编号 | MFCD00056776 |
| PubChem化学物质编号 | 24278343 |
| NACRES | NA.85 |
产品性质
| 质量水平 | 200 |
| 形式 | powder or crystals |
| 作用机制 | DNA synthesis | interferes enzyme | inhibits |
| 抗生素抗菌谱 | Gram-negative bacteria |
| SMILES string | CCN1N=C(C(O)=O)C(=O)c2cc3OCOc3cc12 |
| InChI | 1S/C12H10N2O5/c1-2-14-7-4-9-8(18-5-19-9)3-6(7)11(15)10(13-14)12(16)17/h3-4H,2,5H2,1H3,(H,16,17) |
| InChI key | VDUWPHTZYNWKRN-UHFFFAOYSA-N |
安全信息
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 2 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | Eyeshields, Gloves, type N95 (US) |
