产品说明
一般描述
24(S)-hydroxycholesterol (24HC) is synthesized from cholesterol in brain dendrites by the action of enzyme cholesterol 24-hydroxylase (CYP46A1). It is catabolized to bile acids in the liver.
应用
24(S)-hydroxycholesterol has been used as an internal standard:
- in ultra-high performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS)
- in liquid chromatography with tandem mass spectrometry (LC-MS/MS) for the quantification of 27-hydroxycholesterol from colorectal tumor samples
- for quantification of human plasma sterols by liquid chromatography with tandem mass spectrometry (LC MS/MS)
生化/生理作用
24(S)-hydroxycholesterol (24HC) elevated levels are reported in liver inflammation and fibrosis. It is a N-methyl-
包装
5 mL Amber Glass Screw Cap Vial (700061P-5mg)
5 mL Amber Glass Screw Cap Vial (700061P-1mg)
基本信息
经验(实验)分子式 | C27H46O2 |
分子量 | 402.65 |
NACRES | NA.25 |
产品性质
测定 | >99% (TLC) |
形式 | powder |
包装 | pkg of 1 × 1 mg (700061P-1mg) pkg of 1 × 5 mg (700061P-5mg) |
manufacturer/tradename | Avanti Polar Lipids 700061P |
运输 | dry ice |
储存温度 | −20℃ |
InChI | 1S/C27H46O2/c1-17(2)25(29)11-6-18(3)22-9-10-23-21-8-7-19-16-20(28)12-14-26(19,4)24(21)13-15-27(22,23)5/h7,17-18,20-25,28-29H,6,8-16H2,1-5H3/t18-,20+,21+,22-,23+,24+,25+,26+,27-/m1/s1 |
InChI key | IOWMKBFJCNLRTC-XWXSNNQWSA-N |
安全信息
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |