产品介绍：
产品说明
一般描述
2-甲基-4-异噻唑啉-3-酮盐酸盐(MIT，甲基异噻唑啉酮)是合成异噻唑啉酮的衍生物。
应用
Methylisothiazolinone (MIT) has been used:
- as a cytotoxic substance to investigate its effect on bronchial epithelial cells (BEAS-2B cells) and its role in apoptotic cell death
- to study the effects of tyrosine phosphorylation on focal adhesion kinase (FAK) activity in the development of neural axons and dendrites
生化/生理作用
2-Methyl-4-isothiazolin-3-one hydrochloride (MIT) is a skin sensitizer known to cause contact dermatitis and allergy. It is extensively used in the cosmetic industry as a preservative. MIT is a neurotoxin and its prolonged exposure may lead to neuronal death and inhibition of neurite outgrowth.
基本信息
| 经验(实验)分子式 | C4H5NOS · HCl |
| 分子量 | 151.61 |
| Beilstein | 3993054 |
| EC 号 | 247-499-3 |
| MDL编号 | MFCD06804636 |
| PubChem化学物质编号 | 24897073 |
产品性质
| 质量水平 | 200 |
| 测定 | ≥99% |
| 作用机制 | protein synthesis | interferes |
| 储存温度 | 2-8℃ |
| SMILES string | Cl[H].CN1SC=CC1=O |
| InChI | 1S/C4H5NOS.ClH/c1-5-4(6)2-3-7-5;/h2-3H,1H3;1H |
| InChI key | SJXPQSRCFCPWQQ-UHFFFAOYSA-N |
安全信息
| 象形图 |    |
| 警示用语： | Danger |
| 危险声明 | H301 - H314 - H317 - H410 |
| 预防措施声明 | P260 - P273 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 |
| 危险分类 | Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Corr. 1A - Skin Sens. 1A |
| 补充剂危害 | EUH071 |
| 储存分类代码 | 6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | Eyeshields, Faceshields, Gloves, type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
