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U-73343

品牌
Sigma-Aldrich
CAS
142878-12-4
货号
U6881
包装型号
规格纯度
参考价格
1572.9 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

U-73343 is used to assess the involvement of G protein-coupled 1-phosphatidylinositol-phosphodiesterase or phospholipase C in receptor-mediated cell activation. It functions downstream of phospholipase C to block receptor-mediated phospholipase D activation.

应用

U-73343 has been used for studying the role of phospholipase C (PLC) signaling in modulating epithelial Na+ channel (ENaC) function in gerbil Reissner′s membranes (RMs). U-73343 has also been used as a negative control for PLC inhibition in mechanically stimulated (MS) and its neighboring (NB) cells.
U-73343 has been used in measuring the fluorescence of intracellular Ca2+.

包装

1, 5 mg in glass bottle

生化/生理作用

Inactive analog of U73122; used as a negative control.

制备说明

U-73343 is soluble in chloroform at 10 mg/ml and yields a clear, colorless to faint yellow solution. It is also soluble in ethanol (0.93 mg/ml) and DMSO (2.3 mg/ml), but is insoluble in water.

基本信息

经验(实验)分子式C29H42N2O3
分子量466.66
MDL编号MFCD00211221
PubChem化学物质编号24900662
NACRESNA.77

产品性质

质量水平200
测定≥98% (HPLC)
形式powder
颜色 white
溶解性DMSO: soluble
SMILES string[H][C@]12CC[C@]3(C)[C@H](CC[C@@]3([H])[C@]1([H])CCc4cc(OC)ccc24)NCCCCCCN5C(=O)CCC5=O
InChI1S/C29H42N2O3/c1-29-16-15-23-22-10-8-21(34-2)19-20(22)7-9-24(23)25(29)11-12-26(29)30-17-5-3-4-6-18-31-27(32)13-14-28(31)33/h8,10,19,23-26,30H,3-7,9,11-18H2,1-2H3/t23-,24-,25+,26+,29+/m1/s1
InChI keyCJHWFIUASFBCKN-ZRJUGLEFSA-N

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备dust mask type N95 (US), Eyeshields, Gloves

Sigma-Aldrich

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