产品说明
一般描述
Pirenzepine dihydrochloride is an anticholinergic agent. It is also considered as an antiulcer drug. It is used to treat myopia, gastric and duodenal ulcers. Pirenzepine dihydrochloride induces the dimerization of muscarinic M1 receptors.
应用
Pirenzepine dihydrochloride has been used
- in transactivation of fibroblast growth factor receptor (FGFR).
- as a supplement in cell culture.
- for the stimulation of human fibroblasts
包装
500 mg in poly bottle
1 g in poly bottle
生化/生理作用
Selective M1 muscarinic acetylcholine receptor antagonist.
特点和优势
This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound is featured on the Acetylcholine Receptors (Muscarinic) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
注意
Hygroscopic; store desiccated at room temperature.
基本信息
| 经验(实验)分子式 | C19H21N5O2 · 2HCl |
| 分子量 | 424.32 |
| EC 号 | 249-907-5 |
| MDL编号 | MFCD00055214 |
| PubChem化学物质编号 | 24277863 |
| NACRES | NA.77 |
产品性质
| 质量水平 | 200 |
| 测定 | ≥98% (TLC) |
| 形式 | powder |
| 颜色 | white |
| 溶解性 | H2O: 50 mg/mL |
| SMILES string | Cl[H].Cl[H].CN1CCN(CC1)CC(=O)N2c3ccccc3C(=O)Nc4cccnc24 |
| InChI | 1S/C19H21N5O2.2ClH/c1-22-9-11-23(12-10-22)13-17(25)24-16-7-3-2-5-14(16)19(26)21-15-6-4-8-20-18(15)24;;/h2-8H,9-13H2,1H3,(H,21,26);2*1H |
| InChI key | FFNMBRCFFADNAO-UHFFFAOYSA-N |
| Gene Information | human ... CHRM1(1128) |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 2 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | Eyeshields, Gloves, type N95 (US) |
