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Elocalcitol

品牌
Sigma-Aldrich
CAS
199798-84-0
货号
SML2395
规格纯度
≥98% (HPLC)
参考价格
1505.69 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

生化/生理作用

Elocalcitol (BX-L628) is an analog of Vitamin D3 that acts as an agonist at vitamin D VDR receptors. It has been shown to inhibit prostate cell growth and RhoA/Rho-kinase signaling. Elocalcitol (BXL-628) downregulated the expression of active RhoA and ROCK activity induced by high glucose and was shown to have renal protective effects.
Elocalcitol is a Vitamin D receptor (VDR) agonist and is an analog of calcitriol. Elocalcitol possesses anti-inflammatory and anti- proliferative properties. It regulates cell apoptosis and cell proliferation by binding to Vitamin D receptors (VDR). It shows a therapeutic effect on people suffering from Benign prostatic hyperplasia (BPH) and lower urinary tract symptoms (LUTS).

基本信息

经验(实验)分子式C29H43FO2
分子量442.65
MDL编号MFCD09954119

产品性质

测定≥98% (HPLC)
形式powder
旋光性[α]/D +97 to +107°, c = c=1 in methanol
颜色 white to beige
溶解性DMSO: 2 mg/mL, clear
储存温度−20℃

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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