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Cyanoborohydride Coupling Buffer

品牌
Sigma-Aldrich
货号
C4187
包装型号
规格纯度
参考价格
3243.18 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

应用

Cyanoborohydride Coupling Buffer is used in affinity chromatography, protein chromatography, activated/functionalized matrices and synthetic reagents. Cyanoborohydride has been used to inform a safe and effective gene-transfer system targeting hepatocytes as well as to develop a method for targeted delivery of anticancer therapeutics to cancer cells in hypoxic areas.
A ready-to-use reagent used to couple amine ligands to aldehyde functional groups. The coupling buffer reaction is a reductive amination of the intermediate Schiff′s base to a stable C−N bond.
Cyanoborohydride Coupling Buffer has been used:

  • in coupling reactions between amines and glutaraldehyde
  • to reduce hydrazone bond to a stable hydrazide bond
  • as a component in oligonucleotide reaction mixture for coverslips functionalization

生化/生理作用

Cyanoborohydride Coupling Buffer is a reagent suitable for reductive amination processes, that contributes to transformation of simple alcohols into more complex amines. It is used in the conversion of Schiff base, by reducing it, to form a secondary amine without affecting aldehyde groups on the support.

组分

0.02 M sodium phosphate, pH 7.5, containing 0.2 M sodium chloride and 3.0 g/L sodium cyanoborohydride

基本信息

NACRESNA.56

产品性质

reaction suitabilityreagent type: reductant
质量水平200
储存温度2-8℃

安全信息

象形图GHS07GHS09
警示用语:Warning
危险声明H302 - H411
预防措施声明P264 - P270 - P273 - P301 + P312 - P391 - P501
危险分类Acute Tox. 4 Oral - Aquatic Chronic 2
储存分类代码12 - Non Combustible Liquids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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