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Decursin

品牌
Sigma-Aldrich
CAS
5928-25-6
货号
SML0786
规格纯度
≥97% (HPLC)
参考价格
1232.73 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

包装

1, 5 mg in glass bottle

生化/生理作用

Decursin is a cumarin isolated from Radix peucedani that exhibits a number of physiological actions including anticancer, antibacterial, antinematodal and antioxidant. Decursin is potent anti-angiogenic agent targeting the VEGFR-2 signaling pathway. Decursin exhibits potent neuroprotective activity against glutamate and Ab- induced neurotoxicity. Apparently, decursin stimulates activation of Nerf2. Also, decursin inhibits androgen stimulated AR translocation to the nucleus in LNCaP prostate cancer cells.

特点和优势

This compound is featured on the Nuclear Receptors (Steroids) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

基本信息

经验(实验)分子式C19H20O5
分子量328.36
NACRESNA.77

产品性质

生物来源Radix peucedani
质量水平100
测定≥97% (HPLC)
形式powder
旋光性[α]/D +120 to +160°, c = 0.5 in chloroform-d
颜色 white to beige
溶解性DMSO: 5 mg/mL, clear
运输wet ice
储存温度−20℃
InChI1S/C19H20O5/c1-11(2)7-18(21)23-16-9-13-8-12-5-6-17(20)22-14(12)10-15(13)24-19(16,3)4/h5-8,10,16H,9H2,1-4H3/t16-/m0/s1
InChI keyCUKSFECWKQBVED-INIZCTEOSA-N

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

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