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Anti-Spectrin antibody produced in rabbit

品牌
Sigma-Aldrich
货号
S1515
规格纯度
whole antiserum
参考价格
5149.17 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Spectrin is the major cytoskeletal component in erythrocytes. It is composed of two types of polypeptides known as α and β with molecular weights of 240 and 220 kDa, respectively. The α- and β-chains form heterotetramers which are linked end-to-end via oligomeric actin and band 4.1 protein.
Spectrin is a multifunctional protein that has lipid-binding sites within CH (calponin-homology) tandem domains, a PH (pleckstrin homology) domain and triple helical segments. It is located on chromosome 1q23.1.

特异性

The antibody reacts specifically with the α and β chains of human erythrocyte spectrin.

免疫原

spectrin from freshly prepared human erythrocyte ghosts.

应用

Anti-Spectrin antibody has been used in western blotting immunofluorescence and immunostaining.

生化/生理作用

The spectrin-based membrane skeleton is essential to provide mechanical stability and membrane integrity. It is also responsible for protein organization, trafficking and resilience of erythrocytes.
Spectrins modulates the cell morphology and mechanical properties. Spectrins also participates in the cell cycle by controlling the upregulation of membrane receptors. α- and β spectrins are essential for the development of nervous system.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

MDL编号MFCD00164739
NACRESNA.41

产品性质

生物来源rabbit
质量水平200
偶联物unconjugated
抗体形式whole antiserum
antibody product typeprimary antibodies
克隆polyclonal
包含15 mM sodium azide
species reactivityhuman
technique(s)western blot: 1:400
UniProt登记号P02549
运输dry ice
储存温度−20℃
Gene Informationhuman ... SPTA1(6708), SPTB(6710), SPTBN1(6711), SPTBN2(6712), SPTBN4(57731), SPTBN5(51332)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKnwg
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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