产品说明

一般描述

Albumin is the most copious protein in blood plasma. Produced in the liver, serum albumin serves as a carrier protein for biomolecules like as fatty acids, amino acids, and steroids.
This human serum albumin (HSA) product has been specially tested and evaluated to be low in the following properties:

• Essentially protease-free / low protease content
• Low alkaline phosphatase content
• Low peroxidase content

Serum albumin is used in various applications related to molecular biology, notably as an inert protein stabilizer for stock solutions of enzymes and proteins of interest. In such applications, it is thus important for the HSA to be protease free, to maintain the integrity of the protein or enzyme of interest.
Protease-free HSA is especially useful for applications like:

• Enzyme assays
• Protein-based assays
• Protease-sensitive techniques such as:

(a) Enzyme immunoassay (EIA)
(b) Nucleic acid hybridization
(c) Radioimmunoassay (RIA)

应用

Albumin was used to test its effect on the in vitro bactericidal activity of cefditoren against penicillin-resistant Streptococcus pneumonia. It has been clinically used in serious and often life-threatening conditions, such as shock and blood loss due to trauma, burns, and surgery.
It was used to test the effect of non-enzymatic glycation on the unfolding of human serum albumin. It was also used to test the two distinct pathways used by intestinal epithelial cells for HLA class II antigen processing.

包装

1 g in glass bottle
500 mg in glass bottle

生化/生理作用

血清白蛋白可作为类固醇、脂肪酸和甲状腺激素的载体蛋白，对调节血液的胶体渗透压至关重要。研究还发现白蛋白可结合外源物质，特别是药物(例如布洛芬、华法林)，并强烈影响其药代动力学。导致白蛋白氧化还原状态变化的氧化应激对其生理功能具有广泛的影响。

特点和优势

• Low protease activity / essentially protease-free (≤ 0.0001 units/mg protein)
• Low alkaline phosphatase activity (≤ 0.001 units/mg protein)
• Low peroxidase activity (≤ 0.001 units/mg protein)

制备说明

Prepared from A1653

其他说明

查看更多关于 人血清白蛋白的信息。

基本信息

EC 号	274-272-6
MDL编号	MFCD00081418
NACRES	NA.25

产品性质

质量水平	200
生物来源	human
测定	≥96% (agarose gel electrophoresis)
形式	lyophilized powder
分子量	monomer calculated mol wt 66478 Da
technique(s)	tissue culture: suitable
杂质	HIV I and HIVII, HCV and HBsAg, tested negative
溶解性	H2O: soluble 50 mg/mL
UniProt登记号	P02768
异质活性	Alkaline phosphatase ≤0.001 units/mg protein Peroxidase ≤0.001 units/mg protein Protease ≤0.0001 units/mg protein
储存温度	2-8℃
Gene Information	human ... ALB(213)

安全信息

储存分类代码	12 - Non Combustible Liquids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	Eyeshields, Gloves