产品说明
一般描述
Albumin (ALB) constitutes 25% of the proteins produced by the liver. It is a protein of a single polypeptide chain with a thiol group. The ALB gene is mapped to human 4q13.3.
应用
Albumin was used to test its effect on the in vitro bactericidal activity of cefditoren against penicillin-resistant Streptococcus pneumonia.
It has been clinically used in serious and often life-threatening conditions, such as shock and blood loss due to trauma, burns, and surgery.
Albumin from human serum has been used:
- in cyclophilin isomerase assay
- as a component in blocking solution for immunogold quantification of amino acids and proteins in complex subcellular compartments
- in G-pseudotyped HIV (PHIV) assay mixture to study its effect on GSK364735 antiviral potency
包装
500 mg in poly bottle
1, 5, 10, 50, 100 g in poly bottle
生化/生理作用
血清白蛋白可作为类固醇、脂肪酸和甲状腺激素的载体蛋白,对调节血液的胶体渗透压至关重要。研究还发现白蛋白可结合外源物质,特别是药物(例如布洛芬、华法林),并强烈影响其药代动力学。导致白蛋白氧化还原状态变化的氧化应激对其生理功能具有广泛的影响。
Albumin serves as a protein repository and functions as a binding and transport protein. Albumin binding dissolves the biomolecules in blood and ensures its effective transport. This prevents the loss of substance through excretion. Pathological conditions like vasculitis, lymphangiectasia, glomerulonephritis, and hepatic sinusoidal hypertension might result in hypoalbuminemia.
质量
Remainder mostly globulins
其他说明
查看更多关于 人血清白蛋白的信息。
基本信息
EC 号 | 274-272-6 |
MDL编号 | MFCD00081418 |
eCl@ss | 42010201 |
NACRES | NA.25 |
产品性质
质量水平 | 300 |
生物来源 | human |
测定 | ≥96% (agarose gel electrophoresis) |
形式 | lyophilized powder |
分子量 | monomer calculated mol wt 66478 Da |
technique(s) | ELISA: suitable tissue culture: suitable western blot: suitable |
杂质 | HIV I and HIVII, HCV and HBsAg, tested negative |
溶解性 | H2O: soluble 50 mg/mL |
UniProt登记号 | P02768 |
储存温度 | 2-8℃ |
Gene Information | human ... ALB(213) |
安全信息
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
个人防护装备 | Eyeshields, Gloves |