产品介绍：
产品说明
一般描述
2,3-Dimethoxy-5-methyl-p-benzoquinone (Coenzyme Q0 or DMM) is present in all the cells including neural cells.
应用
Coenzyme Q0 inhibits (via radical quenching) reactions of gamma-irradiation induced homolytic cleavage of O-glycoside bonds in polysaccharides. Coenzyme Q0 induces apoptosis and modulates the cell cycle in estrogen receptor negative breast cancer cells. It is toxic to other cells such as insulin producing cells.
2,3-Dimethoxy-5-methyl-p-benzoquinone has been used:
- as a tau protein fibrillization inducer to determine the regions of tau involved in the formation of paired helical filaments (PHFs)
- as a component in buffer B for cytochrome oxidation assay with subsaturating light
- in the RPMI-1640 medium for 2,3-bis-(2-methoxy-4-nitro-5-sulphenyl)-(2H)-tetrazolium-5-carboxanilide (XTT) assay to quantify antifungal activity
包装
1, 5 g in glass bottle
生化/生理作用
2,3-Dimethoxy-5-methyl-p-benzoquinone (Coenzyme Q0) interacts with tau protein and aids in the formation of filamentous structure.
基本信息
| 经验(实验)分子式 | C9H10O4 |
| 分子量 | 182.17 |
| Beilstein | 1640422 |
| EC 号 | 210-100-8 |
| MDL编号 | MFCD00001595 |
| PubChem化学物质编号 | 24894261 |
产品性质
| 质量水平 | 200 |
| mp | 58-60 ℃ (lit.) |
| 储存温度 | 2-8℃ |
| SMILES string | COC1=C(OC)C(=O)C(C)=CC1=O |
| InChI | 1S/C9H10O4/c1-5-4-6(10)8(12-2)9(13-3)7(5)11/h4H,1-3H3 |
| InChI key | UIXPTCZPFCVOQF-UHFFFAOYSA-N |
安全信息
| 象形图 |  |
| 警示用语： | Warning |
| 危险声明 | H315 - H319 - H335 |
| 预防措施声明 | P302 + P352 - P305 + P351 + P338 |
| 危险分类 | Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3 |
| 靶器官 | Respiratory system |
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 2 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | dust mask type N95 (US), Eyeshields, Gloves |
