产品介绍：
产品说明
一般描述
N-Butyldeoxynojirimycin is an alkylated product of imino sugar deoxynojirimycin.
应用
N-Butyldeoxynojirimycin has been used:
- in the inhibition of glycolipid synthesis in neuroblastoma cells
- in the inhibition the ceramide-specific glycosyltransferase in hepatocytes
- in the inhibition of β-glucosidase (GBA2) using fluorescence- activity assay in human embryonic kidney (HEK293) cells.
包装
1, 5 mg in glass bottle
生化/生理作用
N-Butyldeoxynojirimycin is an inhibitor of glucosyltransferase and α-glucosidases. N-Butyldeoxynojirimycin, also known as misglustat, reduces glycolipid levels by substrate reduction therapy (SRT) and is effectively used for the treatment of glycosphingolipid lysosomal storage disorder, Gaucher disease.
α-glucosidase Inhibitor
基本信息
| 经验(实验)分子式 | C10H21NO4 |
| 分子量 | 219.28 |
| MDL编号 | MFCD00272581 |
| PubChem化学物质编号 | 24892070 |
| NACRES | NA.32 |
产品性质
| 测定 | ≥98% (TLC) |
| 质量水平 | 200 |
| 形式 | film (dried in situ) |
| 溶解性 | water: 9.80-10.20 mg/mL, clear, colorless |
| 储存温度 | 2-8℃ |
| SMILES string | CCCCN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO |
| InChI | 1S/C10H21NO4/c1-2-3-4-11-5-8(13)10(15)9(14)7(11)6-12/h7-10,12-15H,2-6H2,1H3/t7-,8+,9-,10-/m1/s1 |
| InChI key | UQRORFVVSGFNRO-UTINFBMNSA-N |
| Gene Information | human ... UGCG(7357) |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | Eyeshields, Gloves, type N95 (US) |
