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Nicotinic Acid

烟酸

品牌
Sigma-Aldrich
CAS
59-67-6
货号
N5410
规格纯度
meets USP testing specifications
参考价格
3341.5 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Nicotinic acid, also referred to as niacin or as vitamin B3, is a water-soluble vitamin. Nicotinic acid is synthesized from the amino acid tryptophan and is present majorly in peanuts, fish and lean meat.

应用

Nicotinic acid has been used as an antioxidant to evaluate its protective functionality in colon LoVo cell lines against doxorubicin induced cytotoxicity.

生化/生理作用

Nicotinic modulates lipid metabolism and may be useful in treating dyslipidemia. It is an antioxidant and acts as a coenzyme in the form of nicotinamide adenine nucleotides. Deficiency of niacin leads to enhanced lipid peroxidation and is also implicated in Crohn′s disease Deficiency also impacts DNA repair and also leads to skin and gastrointestinal disorder, pellagra. Nicotinic acid reduces the low-density lipoprotein (LDL) synthesis and improves high-density lipoprotein (HDL) levels.

基本信息

经验(实验)分子式C6H5NO2
分子量123.11
Beilstein109591
EC 号200-441-0
MDL编号MFCD00006391
PubChem化学物质编号24897734
NACRESNA.21

产品性质

质量水平200
生物来源synthetic (organic)
agencyUSP/NF
meets USP testing specifications
测定99.0-101.0% dry basis
形式powder
颜色 white
mp236-239 ℃ (lit.)
application(s)pharmaceutical (small molecule)
SMILES stringOC(=O)c1cccnc1
InChI1S/C6H5NO2/c8-6(9)5-2-1-3-7-4-5/h1-4H,(H,8,9)
InChI keyPVNIIMVLHYAWGP-UHFFFAOYSA-N
Gene Informationhuman ... CYP1A2(1544)
rat ... Chrnb2(54239)

安全信息

象形图GHS07
警示用语:Warning
危险声明H319
预防措施声明P280 - P305 + P351 + P338 - P337 + P313
危险分类Eye Irrit. 2
储存分类代码13 - Non Combustible Solids
WGKWGK 1
闪点(F)379.4 °F - closed cup
闪点(C)193 ℃ - closed cup
个人防护装备dust mask type N95 (US), Eyeshields, Gloves

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