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Flunarizine dihydrochloride

氟桂嗪 二盐酸盐

品牌
Sigma-Aldrich
CAS
30484-77-6
货号
F8257
规格纯度
≥98% (TLC)
参考价格
787.61 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Flunarizine has antihistamine, anticonvulsant and vestibular depressive properties. It protects endothelial cells from calcium overload-induced damage. Flunarizine is used to treat epilepsy, migraine prophylaxis, cerebral blood flow disturbances, peripheral vascular disease and vertigo.

应用

Flunarizine dihydrochloride has been used to study the effect of flunarizine on epileptiform activity. It is also used to study its effect on high-potassium induced increase of intracellular free calcium.

包装

1, 10 g in poly bottle

生化/生理作用

阻断 T 型 Ca2+/Na+ 通道;抑制嗜铬细胞中由 K+ 诱导的儿茶酚胺释放。

特点和优势

This compound was developed by Johnson & Johnson. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

基本信息

经验(实验)分子式C26H26F2N2 · 2HCl
分子量477.42
Beilstein4284243
EC 号250-216-6
MDL编号MFCD00058198
PubChem化学物质编号24277835
NACRESNA.77

产品性质

质量水平200
测定≥98% (TLC)
创始人Johnson & Johnson
储存温度2-8℃
SMILES stringCl[H].Cl[H].Fc1ccc(cc1)C(N2CCN(CC2)C\C=C\c3ccccc3)c4ccc(F)cc4
InChI1S/C26H26F2N2.2ClH/c27-24-12-8-22(9-13-24)26(23-10-14-25(28)15-11-23)30-19-17-29(18-20-30)16-4-7-21-5-2-1-3-6-21;;/h1-15,26H,16-20H2;2*1H/b7-4+;;
InChI keyRXKMOPXNWTYEHI-RDRKJGRWSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H302
预防措施声明P264 - P270 - P301 + P312 - P501
危险分类Acute Tox. 4 Oral
储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备dust mask type N95 (US), Eyeshields, Gloves

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