产品说明
应用
This heterobifunctional, PEGylated crosslinker features a carboxylic acid at one end and Boc-protected amino group at the other, which can be deprotected with mildly acidic conditions. The hydrophillic PEG linker facilitates solubility in biological applications. BocNH-PEG4-acid can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC® molecules) for targeted protein degradation
其他说明
A Hexylchloride-Based Catch-and-Release System for Chemical Proteomic Applications
A Biocompatible Condensation Reaction for the Labeling of Terminal Cysteine Residues on Proteins
法律信息
PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license
基本信息
| 经验(实验)分子式 | C15H29NO8 |
| 分子量 | 351.39 |
产品性质
| 形式 | liquid |
| reaction suitability | reaction type: Pegylations reagent type: cross-linking reagent |
| 折射率 | n |
| 密度 | 1.1395 g/mL |
| 储存温度 | −20℃ |
| SMILES string | OC(COCCOCCOCCOCCNC(OC(C)(C)C)=O)=O OC(COCCOCCOCCOCCNC(OC(C)(C)C)=O)=O |
安全信息
| 储存分类代码 | 10 - Combustible liquids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
