产品说明
应用
This heterobifunctional, PEGylated crosslinker features an amino group at one end and t-butyl-protected carboxyl group at the other, which can be deprotected with acidic conditions. The hydrophillic PEG linker facilitates solubility in biological applications. Amino-PEG6-t-butyl ester can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC® molecules) for targeted protein degradation.
法律信息
PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license
基本信息
| 经验(实验)分子式 | C19H39NO8 |
| 分子量 | 409.51 |
| MDL编号 | MFCD13184944 |
产品性质
| 形式 | liquid |
| reaction suitability | reagent type: cross-linking reagent |
| 折射率 | n |
| 密度 | 1.06581 g/mL |
| 储存温度 | −20℃ |
| SMILES string | NCCOCCOCCOCCOCCOCCOCCC(OC(C)(C)C)=O NCCOCCOCCOCCOCCOCCOCCC(OC(C)(C)C)=O |
安全信息
| 储存分类代码 | 10 - Combustible liquids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
