产品介绍：
产品说明
应用
Bisindolylmaleimide II (BIS II) has been used:
- as a protein kinase C (PKC) inhibitor to study its effects on cardiomyocyte phenotypes
- as a PKC inhibitor along with methanandamide (mAEA) to study its effects on murine gastric vagal afferent (GVA) mechanosensitivity
- as a PKC/protein kinase A (PKA) inhibitor to study its effects on bone-marrow cells
生化/生理作用
Bisindolylmaleimide II (BIS II) acts as a dual protein kinase A/C (PKA/C) inhibitor.
基本信息
| 经验(实验)分子式 | C27H26N4O2 |
| 分子量 | 438.52 |
| MDL编号 | MFCD00236430 |
| PubChem化学物质编号 | 329773212 |
产品性质
| 质量水平 | 200 |
| 生物来源 | synthetic (organic) |
| 测定 | ≥97% (Mixture of 2 isomers) |
| 形式 | powder |
| 溶解性 | DMSO: soluble ethanol: soluble |
| 运输 | dry ice |
| 储存温度 | −20℃ |
| SMILES string | CN1CCCC1CCn2cc(C3=C(C(=O)NC3=O)c4c[nH]c5ccccc45)c6ccccc26 |
| InChI | 1S/C27H26N4O2/c1-30-13-6-7-17(30)12-14-31-16-21(19-9-3-5-11-23(19)31)25-24(26(32)29-27(25)33)20-15-28-22-10-4-2-8-18(20)22/h2-5,8-11,15-17,28H,6-7,12-14H2,1H3,(H,29,32,33) |
| InChI key | LBFDERUQORUFIN-UHFFFAOYSA-N |
安全信息
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | Eyeshields, Gloves, type N95 (US) |
