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Urokinase Inhibitor Screening Kit

尿激酶抑制剂筛选试剂盒

品牌
Sigma-Aldrich
货号
MAK220
规格纯度
Sufficient for 100 Fluorometric tests
参考价格
6884.17 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Urokinase (Urokinase-type plasminogen activator, uPA, EC 3.4.21.73) is a serine protease involved in the degradation of extracellular matrix components. It cleaves the Arg-Val bond in plasminogen and converts it to plasmin. The activity of uPA is important in tumor cell proliferation and migration. Polymorphisms in uPA gene are reportedly associated with Alzheimer′s disease.

适用性

适于筛选尿激酶抑制剂。

原理

The Urokinase Inhibitor Screening Kit is a rapid, simple and sensitive assay that is suitable for the screening of Urokinase inhibitors. Urokinase activity is measured by cleaving a synthetic 7-amino-4-trifluoromethylcoumarin (AFC)-based substrate to yield AFC, a fluorescent product (λex = 350/ λem = 450 nm), proportional to the enzymatic activity present.

基本信息

NACRESNA.25

产品性质

detection methodfluorometric
储存温度−20℃
Gene Informationhuman ... PLAU(5328)
mouse ... PLAU(18792)
rat ... PLAU(25619)

组份列表

组份不可单独销售

货号组份
Urokinase Assay Buffer
Urokinase Substrate
Human Urokinase
Urokinase Inhibitor; 10 mM GGACK Dihydrochloride

安全信息

象形图GHS08
警示用语:Danger
危险声明H334
预防措施声明P261 - P284 - P501
危险分类Resp. Sens. 1
储存分类代码10 - Combustible liquids
WGKWGK 3

Sigma-Aldrich

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