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Sphingomyelin Quantification Colorimetric Assay Kit

鞘磷脂含量检测试剂盒(比色法)

品牌
Sigma-Aldrich
货号
MAK262
规格纯度
sufficient for 100 colorimetric tests
参考价格
4468.54 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Sphingomyelin, a sphingolipid consisting of a phospholipid (typically phosphocholine) attached to a ceramide moiety, is a major component of cellular membranes. Sphingomyelin is enriched in the exoplasmic leaflet of the cell membrane. Within the cell membrane, sphingomyelin interacts with cholesterol to form lipid rafts. The metabolism of sphingomyelin contributes to cellular signaling via the release of ceramide, a second messenger that participates in multiple cellular signaling pathways. Sphingomyelin accumulates in Niemann-Pick disease due to deficiencies in sphingomyelinase activity. Increased levels of sphingomyelin is observed in hypercholesterolemia, which is characterized by the accumulation of sphingomyelin in arteriosclerotic lesions resulting in ischemic heart disease.

适用性

Suitable for quantifying sphingomyelin in serum, plasma, and other biological fluids, and tissue and cell culture samples.

原理

The Sphingomyelin Quantification Assay Kit is a simple and sensitive method for quantifying sphingomyelin. The assay is based on the hydrolysis of sphingomyelin into ceramide and phosphocholine by sphingomyelinase. Alkaline phosphatase (ALP) dephosphorylates phosphocholine to choline producing a reaction that generates a colorimetric signal (A570). The assay is sensitive to 1 M of sphingomyelin in a variety of samples.

基本信息

NACRESNA.84

产品性质

detection methodcolorimetric
储存温度−20℃

安全信息

象形图GHS05GHS07GHS08GHS09
警示用语:Danger
危险声明H312 - H317 - H318 - H334 - H361d - H410
预防措施声明P202 - P273 - P280 - P302 + P352 + P312 - P305 + P351 + P338 - P308 + P313
危险分类Acute Tox. 4 Dermal - Aquatic Acute 1 - Aquatic Chronic 2 - Eye Dam. 1 - Repr. 2 - Resp. Sens. 1 - Skin Sens. 1
储存分类代码10 - Combustible liquids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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