产品说明
一般描述
Sphinganine-d7 is a deuterated derivative of sphinganine. Sphinganine, also called as dihydrosphingosine is a derivative of sphingosine. Sphinganines are produced in endoplasmic reticulum, by decarboxylating condensation of palmitoyl-CoA and serine.
应用
Sphinganine-d7 has been used as an internal standard for quantification of sphingolipid concentrations in plasma and tissue samples by high-performance liquid chromatography tandem mass spectrometry.
生化/生理作用
Sphinganine (SPA) acts as a selective inhibitor of protein kinase C in intact human neutrophils. It may function a potential biomarker for the diagnosis of sphingolipidoses. SPA accumulation enables fumonisin B1 to stimulate apoptosis. It also has an ability to block cholesterol transport in Niemann-Pick Type C (NPC) disease.
包装
5 mL Amber Glass Screw Cap Vial (860658P-1mg)
基本信息
| 经验(实验)分子式 | C18H32D7NO2 |
| 分子量 | 308.55 |
| NACRES | NA.25 |
产品性质
| 形式 | powder |
| 包装 | pkg of 1 × 1 mg (860658P-1mg) |
| manufacturer/tradename | Avanti Polar Lipids 860658P |
| 运输 | dry ice |
| 储存温度 | −20℃ |
| SMILES string | OC[C@@](N)([H])[C@@](O)([H])CCCCCCCCCCCCC(C(C([2H])([2H])[2H])([2H])[2H])([2H])[2H] |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
