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Purvalanol A

品牌
Sigma-Aldrich
CAS
212844-53-6
货号
P4484
规格纯度
≥98% (HPLC), powder
参考价格
1674.67 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

包装

1 mg in glass bottle

生化/生理作用

Purvalanol A is found to inhibit ABCG2 (ATP-binding cassette G2) transporter in vitro. It is also known to attenuate cellular Src kinase action and induce cell cycle arrest at the G2 to M phase transition.
Purvalanol A is a potent, cell-permeable cyclin-dependent protein kinase (cdk) inhibitor.

特点和优势

This compound is featured on the CDKs page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

基本信息

经验(实验)分子式C19H25ClN6O
分子量388.89
MDL编号MFCD02179211
PubChem化学物质编号24898543
NACRESNA.77

产品性质

质量水平200
测定≥98% (HPLC)
形式powder
溶解性methylene chloride: 50 mg/mL
运输dry ice
储存温度−20℃
SMILES stringCC(C)[C@H](CO)Nc1nc(Nc2cccc(Cl)c2)c3ncn(C(C)C)c3n1
InChI1S/C19H25ClN6O/c1-11(2)15(9-27)23-19-24-17(22-14-7-5-6-13(20)8-14)16-18(25-19)26(10-21-16)12(3)4/h5-8,10-12,15,27H,9H2,1-4H3,(H2,22,23,24,25)/t15-/m0/s1
InChI keyPMXCMJLOPOFPBT-HNNXBMFYSA-N

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, type N95 (US)

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