产品说明
一般描述
N-palmitoyl serine phosphoric acid prevents human platelet aggregation, which is induced by 1-hexadecyl-2-lyso-sn-glycero-3-phosphate.
Lysophosphatidic acid (LPA) receptor modulators include N-palmitoyl serine phosphoric acid and N-palmitoyl-tyrosine phosphoric acid. N-palmitoyl serine phosphoric acid is a competitive inhibitor of the LPA receptor in Xenopus oocytes. However, in mammalian cells, N-palmitoyl-serine phosphoric acid may act as an agonist for the LPA receptor. LPA is a lipid mediator that acts similar to growth factors through G-protein coupled plasma membrane receptors. LPA may play a role in platelet aggregation, smooth muscle contraction, vasoactive changes, cytoskeletal reorganization and cell proliferation. N-palmitoyl serine phosphoric acid may also play a role in signal transduction in mammalian cells by increasing intracellular calcium.
包装
5 mL Amber Glass Screw Cap Vial (800715P-1mg)
制备说明
Product use: A range of 0.1-20 mM of N-palmitoyl serine phosphoric acid can be used for cell studies. Make a stock solution of 5 mM in DMSO and store at -20℃. Diluted N-palmitoyl serine phosphoric acid can be directly added to the study medium. An et al. dissolved N-palmitoyl-serine and N-palmitoyl-tyrosine phosphoric acid in 0.1 mL PBS containing 0.1 mg/mL human serum albumin before adding to cells. In X. laevis studies, these LPA inhibitors were dissolved in DMSO at 1 mM and filtered through a 0.45 mM membrane filter before injection.
基本信息
| 经验(实验)分子式 | C19H44N3O7P |
| 分子量 | 457.54 |
| NACRES | NA.25 |
产品性质
| 测定 | >99% (TLC) |
| 形式 | powder |
| 包装 | pkg of 1 × 1 mg (800715P-1mg) |
| manufacturer/tradename | Avanti Polar Lipids 800715P |
| 运输 | dry ice |
| 储存温度 | −20℃ |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
