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N-C12-desoxymethylsphinganine

品牌
Avanti
CAS
1246298-41-8
货号
860461P
规格纯度
N-lauroyl-1-desoxymethylsphinganine (m17:0/12:0), powder
参考价格
3574.44 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

N-C12-desoxymethylsphinganine commonly referred to as 1-deoxydihydroceramide (1-deoxyDHCer), is the N-acylated form of 1-deoxysphinganine, a potent inhibitor of sphingolipid metabolism.
Commonly referred to as 1-desoxymethyldihydroceramide (1-desoxyMeDHCer), this product is the N-acylated form of 1-desoxymethylsphinganine, a potent inhibitor of sphingolipid metabolism. The biological activity of 1-desoxyMeDHCer is not clearly understood at this time.

生化/生理作用

Ceramide synthases (CerS) catalyzes the acylation of sphingoid bases using fatty acyl-CoA and its inhibition results in decrease of desoxymethylsphinganine (N-acylsphinganines (dihydroceramides)) levels and accumulation of sphinganine (Sa). Dihydroceramides (DHCer) are intermediates of ceramide biosynthesis.

包装

5 mL Amber Glass Screw Cap Vial (860461P-1mg)

基本信息

经验(实验)分子式C29H59NO2
分子量453.78

产品性质

测定>99% (TLC)
形式powder
包装pkg of 1 × 1 mg (860461P-1mg)
manufacturer/tradenameAvanti Polar Lipids 860461P
运输dry ice
储存温度−20℃

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3

Sigma-Aldrich

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