产品介绍:
产品说明
生化/生理作用
MMK-1 is a potent and selective FPR2 (FPRL-1) agonist (Ca2+ flux EC50 <2 nM/FPR2 vs. >10 μM/FPR1 with respective HEK293 transfectants) and an effective calcium-mobilizing and chemotactic agent for human monocytes & neutrophils (1-1000 nM). MMK-1 increases pertussis toxin-sensitive inflammatory cytokines production in human monocyte cultures (50 ng/mL PT & 10 μM MMK-1), exerts anxiolytic-like activities in mice (100 pmol/mouse icv) and shows anti-alopecia efficacy in rats in vivo (100 mg/kg p.o. or 10 mg/kg i.p.).
基本信息
经验(实验)分子式 | C75H123N19O18S · xC2HF3O2 |
分子量 | 1610.96 (free base basis) |
产品性质
质量水平 | 100 |
测定 | ≥95% (HPLC) |
形式 | film or powder |
颜色 | white to beige |
储存温度 | −20℃ |