产品说明
一般描述
Compounds are arranged in 96-well format in 16 racks of 80, one compound per well (250 μl at 10 mM in DMSO).
应用
LOPAC®1280 has been used:
- in the screening of novel inhibitors for chemotaxis/ migration using Dictyostelium as a model
- to test the ability to modulate and to measure forskolin-stimulated cAMP levels in CHO-hCB2 cells and to modulate ligand-induced receptor/β-arrestin interaction
- in screening of small molecules for activating bone morphogenetic protein (BMP) signaling
- in screening of compounds that plays a role in regulating subcellular localization of nitric oxide associated protein 1 (NOA1) protein
特点和优势
Includes the latest, drug-like molecules in the fields of Cell Signaling & Neuroscience:
- Apoptosis
- G Proteins & Cyclic Nucleotides
- Gene Regulation & Expression
- Ion Channels
- Lipid Signaling
- Multi-Drug Resistance
- Neurotransmission
- Phosphorylation
SDFile provided to construct a database containing:
- Structure
- Primary Name
- Secondary Name
- Pharmacological Activity
- Product Number
- Rack Position
To request a list of components, please visit sigma.com/LOPAC
Collection of 1,280 Pharmacologically-Active Sigma Compounds
其他说明
For sale in the U.S. only. Customers outside of the U.S. should refer to product code LO3300.
法律信息
LOPAC is a registered trademark of sigma-aldrich Co. LLC
产品性质
质量水平 | 100 |
运输 | dry ice |
储存温度 | −20℃ |
安全信息
象形图 | |
警示用语: | Danger |
危险声明 | H300 + H310 + H330 - H315 - H317 - H318 - H334 - H340 - H350 - H360FD - H362 - H371 - H373 - H410 |
预防措施声明 | P263 - P273 - P280 - P302 + P352 + P310 - P304 + P340 + P310 - P305 + P351 + P338 |
危险分类 | Acute Tox. 1 Inhalation - Acute Tox. 2 Dermal - Acute Tox. 2 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1A - Eye Dam. 1 - Lact. - Muta. 1B - Repr. 1A - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 2 - STOT SE 2 |
储存分类代码 | 6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials |
WGK | WGK 3 |
闪点(F) | 188.6 °F - closed cup |
闪点(C) | 87 ℃ - closed cup |