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Human MMP-13 ELISA Kit

品牌
Sigma-Aldrich
货号
RAB0364
规格纯度
for serum, plasma, cell culture supernatant and urine
参考价格
7469.3 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

The Human MMP-13 ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human MMP-13 in serum, plasma, cell culture supernatants and urine.

免疫原

Recombinant Human MMP13

应用

请参考Protocol了解详情。

生化/生理作用

MMP13 (matrix metalloproteinase 13) functions against different types of ECM (extracellular matrix) components. It gets activated by and activates multiple MMPs and hence, has a central role in the MMP cascade. This protein is frequently expressed in colorectal cancer (CRC) and this expression is linked with poor survival in CRC. MMP13 expression is absent in normal breast tissue, but is present in breast carcinoma suggesting its role in tumorigenesis. The expression of this protein can serve as a marker for tumor invasiveness, as its expression is induced during metastasis of multiple types of cancers, including squamous cell carcinomas of the head and neck and this expression is usually linked to poor prognosis. Missense mutation in this gene results in the autosomal dominant disorder called Missouri type of human spondyloepimetaphyseal dysplasia (SEMDMO), which is characterized by abnormal growth and modeling of vertebrae and long bones.

其他说明

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

基本信息

NACRESNA.32

产品性质

species reactivityhuman
包装kit of 96 wells (12 strips x 8 wells)
technique(s)ELISA: suitable
capture ELISA: suitable
inputsample type cell culture supernatant(s)
sample type serum
sample type plasma
sample type urine
assay rangeinter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 6 pg/mL
standard curve range: 8.23-6000 pg/mL
detection methodcolorimetric
运输wet ice
储存温度−20℃
Gene Informationhuman ... MMP13(4322)

组份列表

组份可单独销售

货号组份
RABELADEELISA 5X Assay/Sample Diluent Buffer E (Item E2)
RABSTOP3ELISA Stop Solution (Item I)
RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)
RABWASH420X Wash Buffer (Item B)

安全信息

象形图GHS05
警示用语:Warning
危险声明H290
预防措施声明P234 - P390
危险分类Met. Corr. 1
储存分类代码8A - Combustible, corrosive hazardous materials
WGKWGK 3

Sigma-Aldrich

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