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Human Carbonic Anhydrase IX ELISA Kit

人碳酸酐酶IX ELISA试剂盒

品牌
Sigma-Aldrich
货号
RAB0036
规格纯度
for serum, plasma, cell culture supernatant and urine
参考价格
7209.4 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Carbonic anhydrase IX (CA9) belongs to the zinc-containing metalloenzymes family. The protein is encoded by the gene mapped to human chromosome 9p. The encoded protein is localized on cell membrane and is characterized with an N-terminal proteoglycan-like domain (PG), a CA catalytic domain (CA), a transmembrane helical segment and a short intra-cytoplasmic tail. CA9 is expressed at very low levels in normal tissues (mostly in gastrointestinal tract), but it is expressed at high level in various cancer tissues, such as renal, lung, cervical, ovarian, esophageal and breast cancer.
The Human CA-IX (Carbonic Anhydrase IX) ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human CA-IX in serum, plasma, cell culture supernatants and urine.

免疫原

Recombinant Human CA9

应用

请参考Protocol了解详情。

生化/生理作用

Carbonic anhydrase IX (CA9) aids in reversible hydration of carbon dioxide to carbonic acid and bicarbonate. CA9 functions as a promising biomarker for diagnosing clear cell renal cell carcinoma (ccRCC), tumor hypoxia and prostate cancer (PC). In addition to pH control, CA9 also plays a vital role in cell proliferation, adhesion and tumor invasion.

其他说明

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

基本信息

NACRESNA.32

产品性质

species reactivityhuman
包装kit of 96 wells (12 strips x 8 wells)
technique(s)ELISA: suitable
capture ELISA: suitable
inputsample type urine
sample type cell culture supernatant(s)
sample type plasma
sample type serum
assay rangeinter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 0.2 pg/mL
standard curve range: 0.205-50 pg/mL
detection methodcolorimetric
运输wet ice
储存温度−20℃
Gene Informationhuman ... CA9(768)

组份列表

组份可单独销售

货号组份
RABELADBELISA 5X Assay/Sample Diluent Buffer B (Item E1)
RABELADCELISA 1X Assay/Sample Diluent Buffer C (Item L)
RABSTOP3ELISA Stop Solution (Item I)
RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)
RABWASH420X Wash Buffer (Item B)

安全信息

象形图GHS05
警示用语:Warning
危险声明H290
预防措施声明P234 - P390
危险分类Met. Corr. 1
储存分类代码8A - Combustible, corrosive hazardous materials
WGKWGK 3

Sigma-Aldrich

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