产品说明
Amino Acid Sequence
Abz-Ser-Asp-Lys-DNP
应用
Abz-SDK(Dnp)P-OH trifluoroacetate is an Angiotensin Converting Enzyme (ACE) fluorescent peptide substrate that specifically binds to the N domain of ACE. Abz-SDK(Dnp)P-OH has been used to study tipifarnib-induced apoptosis in acute myeloid leukemia and multiple myeloma cells.
包装
1 mg in glass bottle
生化/生理作用
Abz-SDK(Dnp)P-OH is an Angiotensin Converting Enzyme (ACE) fluorescent peptide substrate specific for the N domain for real time fluorescent assay (ACE, Peptidyl Dipeptidase, Kininase II, E.C. 3.4.15.1).
特点和优势
This compound is featured on the Angiotensin Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
基本信息
经验(实验)分子式 | C31H38N8O13 · xC2HF3O2 |
分子量 | 730.68 (free base basis) |
MDL编号 | MFCD09753055 |
PubChem化学物质编号 | 24891013 |
产品性质
质量水平 | 100 |
测定 | ≥91% (HPLC) |
形式 | lyophilized powder |
溶解性 | H2O: freely soluble |
储存温度 | 2-8℃ |
SMILES string | OC(=O)C(F)(F)F.Nc1ccccc1C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCCNc2ccc(cc2[N+]([O-])=O)[N+]([O-])=O)C(=O)N3CCC[C@H]3C(O)=O |
InChI | 1S/C31H38N8O13.C2HF3O2/c32-19-7-2-1-6-18(19)27(43)36-23(16-40)29(45)35-22(15-26(41)42)28(44)34-21(30(46)37-13-5-9-24(37)31(47)48)8-3-4-12-33-20-11-10-17(38(49)50)14-25(20)39(51)52;3-2(4,5)1(6)7/h1-2,6-7,10-11,14,21-24,33,40H,3-5,8-9,12-13,15-16,32H2,(H,34,44)(H,35,45)(H,36,43)(H,41,42)(H,47,48);(H,6,7)/t21-,22-,23-,24-;/m0./s1 |
InChI key | IFSUGURCQHMSJS-JPIABUGISA-N |
安全信息
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |