产品介绍：
产品说明
一般描述
4β-hydroxycholesterol (4β-HC) is a catabolic product of cholesterol metabolism mediated by the enzyme cytochrome P450 family 3 subfamily A member 4 (CYP3A4). 4β-hydroxycholesterol-d7 is the deuterated form of 4β-hydroxycholesterol.
应用
4β-hydroxycholesterol-d7 has been used:
- as an internal standard to spike plasma samples ultra-high-pressure liquid,chromatography–tandem mass spectrometry (UHPLC-MS/MS) analysis
- to spike serum samples for mass spectrometry measurements
- as an internal standard for the quantification of human colon biopsies samples using HPLC-MS
生化/生理作用
4β-hydroxycholesterol (4β-HC) may function as a liver X receptor ligand. The levels of 4β-HC are elevated in dextran sulfate induced colitis along with other oxysterols and it may promote colon inflammation.
包装
5 mL Amber Glass Screw Cap Vial (700042P-1mg)
基本信息
| 经验(实验)分子式 | C27H39O2D7 |
| 分子量 | 409.70 |
| NACRES | NA.25 |
产品性质
| 测定 | >99% (TLC) |
| 形式 | powder |
| 包装 | pkg of 1 × 1 mg (700042P-1mg) |
| manufacturer/tradename | Avanti Polar Lipids 700042P |
| 运输 | dry ice |
| 储存温度 | −20℃ |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
