产品说明
包装
1 mg in glass bottle
生化/生理作用
Prosaptide Tx 14(A) is a potent agonist of G protein-coupled receptors GPR37 (also known as Parkin-associated endothelin receptor-like receptor Pael-R) and GPR37L1. Prosaptide Tx 14(A) is the active fragment of prosaposin, a secreted neuroprotective and glioprotective factor. Prosaptide Tx 14(A) has EC50 values of 5 nM for GPR37L1 and 7 nM for GPR37, and has also been shown to have some GSK3 inhibitory properties. Prosaptide has been shown to improve nerve regeneration in diabetic rats, to reduce neuropathic pain, and to protect dopaminergic neurons in animal models of Parkinson disease.
基本信息
经验(实验)分子式 | C69H110N16O26 · xC2HF3O2 |
分子量 | 1579.70 (free base basis) |
产品性质
质量水平 | 100 |
测定 | ≥95% (HPLC) |
形式 | powder |
颜色 | white to off-white |
运输 | wet ice |
储存温度 | −20℃ |
安全信息
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |