产品说明
一般描述
Lysophosphatidic acid (LPA) receptor modulators include N-palmitoyl serine phosphoric acid and N-palmitoyl-tyrosine phosphoric acid. N-palmitoyl serine phosphoric acid and N-palmitoyl-tyrosine phosphoric acid are competitive inhibitors of the LPA receptor in Xenopus oocytes. However, in mammalian cells, N-palmitoyl-tyrosine phosphoric acid may act as an agonist for the LPA receptor. LPA is a lipid mediator that acts similar to growth factors through G-protein coupled plasma membrane receptors. LPA may play a role in platelet aggregation, smooth muscle contraction, vasoactive changes, cytoskeletal reorganization and cell proliferation.
包装
5 mL Amber Glass Screw Cap Vial (800725P-1mg)
制备说明
Product use: N-palmitoyl-serine and N-palmitoyl-tyrosine phosphoric acid can be used for cell studies. dissolved these lipids in 0.1 mL PBS containing 0.1 mg/mL human serum albumin before adding to cells. In X. laevis studies, these LPA inhibitors were dissolved in DMSO at 1 mM and filtered through a 0.45 mM membrane filter before injection.
基本信息
经验(实验)分子式 | C25H48N3O7P |
分子量 | 533.64 |
NACRES | NA.25 |
产品性质
测定 | >99% (TLC) |
形式 | powder |
包装 | pkg of 1 × 1 mg (800725P-1mg) |
manufacturer/tradename | Avanti Polar Lipids 800725P |
运输 | dry ice |
储存温度 | −20℃ |
安全信息
储存分类代码 | 13 - Non Combustible Solids |