产品说明
一般描述
The bicelle kit is designed to aid with the production of high-quality membrane protein crystals. Bicelles can be integrated into standard crystallization protocols, and in contrast to micelles, bicelles maintain the protein in a more native bilayer environment allowing proteins to be captured in a more biologically relevant orientation.
Bicelle kit contains 200mg of dimyristoylphosphatidylcholine (DMPC), 200mg of dimyristoylphosphatidylglycerol (DMPG), 1g of 3-[(3-cholamidopropyl)-dimethylammonio]-1-propane sulfonate (CHAPS) and 1g of 3-(cholamidopropyl)dimethylammonio-2-hydroxy-1-propane-sulfonate (CHAPSO). Bicelle is a discoidal lipid aggregate. A bicelle consists of a planar bilayer at the center made of long-chain phospholipids, which are encircled by a detergent layer. The planar bilayer is generally composed of DMPC, which may have phospholipids such as (DMPG) for alteration of charge of the membrane. The detergent layer is composed of bile salt derivative, such as CHAPSO.
生化/生理作用
Bicelles acts as membrane mimetics and facilitate membrane-associated biomolecules study.
包装
Package contains 200MG of DMPC, 200MG of DMPG, 1G of CHAPS, and 1G of CHAPSO
20ML Clear Glass Screw Cap Vial for each component (850563P-1EA)
产品性质
形式 | powder |
manufacturer/tradename | Avanti Polar Lipids |
technique(s) | thin layer chromatography (TLC): 99% |
运输 | dry ice |
储存温度 | −20℃ |
安全信息
储存分类代码 | 10 - Combustible liquids |