产品说明
一般描述
The ANP Enzyme Immunoassay (EIA) Kit is an in vitro quantitative assay for detecting ANP peptide based on the principle of Competitive Enzyme Immunoassay. EIA-ANP-1 targets the common sequence of human, mouse and rat, and thus may be used to detect ANP expression in all these species with high specificity and sensitivity.
免疫原
Atrial Natriuretic Peptide, synthetic peptide
应用
For research use only. Not for use in diagnostic procedures.
Atrial Natriuretic Peptide EIA Kit has been used to measure ANP levels in diabetes mellitus patients.
Atrial Natriuretic Peptide EIA Kit has been used for the quantification of atrial natriuretic peptide (ANP) in cell culture.
生化/生理作用
Atrial natriuretic peptide (ANP) is a polypeptide hormone released in response to atrial dilation and it stimulates diuresis, natriuresis and vasorelaxation. ANP acts as an inhibitor of renin-angiotensin-aldosterone system (RAAS) pathway. It also has a major role in body fluid homeostasis and maintenance of blood pressure. Binding of ANP to receptors on target cell stimulate the production of cyclic guanosine monophosphate (GMP). Overexpression of ANP leads to congestive heart failure in the human. Experimental studies show that ANP can be used as a therapeutic for stimulating angiogenesis in ischemic tissues. N-terminal ANP prohormone functions as a biomarker for asymptomatic systolic left ventricular (LV) dysfunction, congestive heart failure and cardiovascular mortality.
基本信息
| NACRES | NA.32 |
产品性质
| species reactivity | rat, human, mouse |
| 包装 | kit of 96 wells (12 strips x 8 wells) |
| technique(s) | ELISA: suitable enzyme immunoassay: suitable |
| input | sample type plasma sample type serum sample type cell lysate sample type culture supernatant(s) |
| assay range | inter-assay cv: <15% intra-assay cv: <10% sensitivity: 1.02 pg/mL standard curve range: 0.1-1000 pg/mL |
| detection method | colorimetric |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... NPPA(4878) |
组份列表
组份可单独销售
| 货号 | 组份 |
| RABHRP3 | HRP-Streptavidin |
安全信息
| 象形图 |  |
| 警示用语： | Warning |
| 危险声明 | H290 |
| 预防措施声明 | P234 - P390 |
| 危险分类 | Met. Corr. 1 |
| 储存分类代码 | 8A - Combustible, corrosive hazardous materials |
| WGK | WGK 3 |
