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2-OHOA

品牌
Avanti
CAS
1229114-68-4
货号
791056P
规格纯度
2-hydroxyoleic acid (sodium salt), powder
参考价格
2073.6 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

2-hydroxyoleic acid (2-OHOA) is a synthetic and non-β oxidation-metabolizable oleic acid derivative. It contains 18 carbon atoms in its fatty acid chain length.

应用

2-hydroxyoleic acid (2-OHOA) is suitable for use:

  • to study its antihypertensive action in adult spontaneously hypertensive rats (SHRs)
  • to study the chemical structure-effect relation of 2-OHOA in the reduction of body weight in rats
  • as an antitumor compound, to study its effect on xenografts lipidome based on imaging mass spectrometry (IMS)

生化/生理作用

2-hydroxyoleic acid (2-OHOA) acts as a potential antihypertensive agent. Oral administration of 2-OHOA is used to reduce body weight.
2-Hydroxy Oleic Acid is an inducer of cell cycle arrest and apoptosis in several cancer cell lines, including glioma, leukemia, breast and colon cancer lines. 2-Hydroxy Oleic Acid increases sphingomyelin (SM) levels in the membranes of tumor cells, which typically display decreased SM membrane content, and remodeled membranes, compared with normal cells. The compound has no effect on SM levels in non-cancer cells.

包装

20 mL Clear Glass Screw Cap Vial (791056P-1g)

基本信息

经验(实验)分子式C18H33NaO3
分子量320.44
NACRESNA.25

产品性质

测定>99% (TLC)
形式powder
包装pkg of 1 × 1 g (791056P-1g)
manufacturer/tradenameAvanti Polar Lipids 791056P
运输dry ice
储存温度−20℃

安全信息

储存分类代码13 - Non Combustible Solids

Sigma-Aldrich

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