产品说明
一般描述
1-desoxymethylsphinganine is synthesized by the condensation of alanine with palmitoyl-CoA.
应用
1-desoxymethylsphinganine is suitable for use for testing its cytotoxic effects on primary neuron-glia cultures. It is also suitable for use as a neurotoxic agent in human CD8+ T cells. In hereditary sensory and autonomic neuropathy type I, mutations in serine palmitoyltransferase long chain base subunit 1 resulting in altered substrate specificity and accumulation of 1.
生化/生理作用
1-desoxymethylsphinganine is neurotoxic towards CD8+ T cells and inhibits cytokine production. However, it is not cytotoxic to dopaminergic neurons.
包装
5 mL Amber Glass Screw Cap Vial (860473P-1mg)
基本信息
经验(实验)分子式 | C17H37NO |
分子量 | 271.48 |
产品性质
形式 | powder |
包装 | pkg of 1 × 1 mg (860473P-1mg) |
manufacturer/tradename | Avanti Polar Lipids 860473P |
运输 | dry ice |
储存温度 | −20℃ |
SMILES string | NC[C@]([H])(O)CCCCCCCCCCCCCCC |
安全信息
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 3 |