产品说明
生化/生理作用
Narasin is a growth-promoting ionophoric antibacterial agent for Enterococci, specifically Enterococcus faecium and Enterococcus faecalis. Narasin inhibits coccidial infection in poultry and mammals and is used in studies involving sodium calcium ion exchange.
In addition, Narasin inhibits Dengue virus (DENV) at the post-entry stage of viral replication during DENV infection. The inhibition of DENV involves a non-cytotoxic mechanism, therefore, Narasin can be possibly considered as therapeutic agent against DENV infection. A dose dependent curve (0.01-5 μM) showed that Narasin has 50% inhibitory concentration at less than 1 μM against all four serotypes of DENV. The IC50 (μM) of Narasin against four different DENV serotypes was 0.05-0.65 μM.
其他说明
Narasin solution is provided at 1.307 mM (1 mg/ml). Typical final concentration for use in cell culture is 0.01-5 μM. Stable at –20 ℃ for at least 2 years.
基本信息
| 经验(实验)分子式 | C43H72O11 |
| 分子量 | 765.03 |
| NACRES | NA.77 |
产品性质
| 质量水平 | 200 |
| 生物来源 | Streptomyces aureofaciens |
| 形式 | solution |
| 浓度 | 1 mg/ml in DMSO |
| 运输 | dry ice |
| 储存温度 | −20℃ |
| InChI | 1S/C43H72O11/c1-12-30(35(46)27(8)34(45)28(9)36-23(4)21-24(5)37(51-36)31(13-2)39(47)48)38-25(6)22-26(7)42(52-38)18-15-32(44)43(54-42)20-19-40(11,53-43)33-16-17-41(49,14-3)29(10)50-33/h15,18,23-34,36-38,44-45,49H,12-14,16-17,19-22H2,1-11H3,(H,47,48)/t23-,24-,25-,26+,27-,28-,29-,30-,31+,32+,33+,34+,36+,37+,38-,40-,41+,42-,43-/m0/s1 |
| InChI key | VHKXXVVRRDYCIK-CWCPJSEDSA-N |
安全信息
| 储存分类代码 | 10 - Combustible liquids |
| WGK | WGK 1 |
| 闪点(F) | 188.6 °F - closed cup |
| 闪点(C) | 87 ℃ - closed cup |
