产品说明
一般描述
Multidrug Resistance-Associated Protein (MRP) is a seven member subfamily of ABC (ATP-binding cassette) transporters. MRP1, 2, and 3 have a similar structure with the ability to transport glutathione and glucuronate conjugates. MRP4 and MRP5 share more structure similarity with each other than with MRP1, 2, and 3. MRP4 and MRP5 also have the ability to transport cyclic nucleotides..The monoclonal anti-MRP3 recognizes human Multidrug Resistance-Associated Protein 3 (MRP3, 190-200 kDA)..
特异性
Reacts with an internal epitope of MRP3. Does not cross-react with the human MDR1, MRP1, MRP2, or MRP5 gene products.
免疫原
fusion protein of MRP3 (amino acids 830-949).
应用
The antibody may be used in immunocytochemistry, immunoblotting, immunohistochemistry.
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunohistochemistry (1 paper)
外形
Supplied in serum-free medium containing 0.7% bovine serum albumin and 0.1% sodium azide.
制备说明
Monoclonal Anti-Multidrug Resistance-Associated Protein 3 (MRP3), mouse isotype IgG1, derived using M3II-21 hybridoma produced by fusion SP2/O mouse myeloma cells and Balb/c mouse lymph nodes cells immunized with amino acids 830-949 of the human MRP3 bacterial fusion protein. The antibody is concentrated from culture supernatant of M3II-21 hybridoma cells grown in a bioreactor.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| MDL编号 | MFCD02263753 |
| NACRES | NA.41 |
产品性质
| 质量水平 | 200 |
| 生物来源 | mouse |
| 偶联物 | unconjugated |
| 抗体形式 | tissue culture supernatant |
| antibody product type | primary antibodies |
| 克隆 | M3II-21, monoclonal |
| 分子量 | antigen 190-200 kDa |
| species reactivity | human |
| 浓度 | 250 μg/mL |
| technique(s) | immunocytochemistry: 1:20-1:50 using acetone- or formaldehyde-fixed cytospin preparations immunohistochemistry (frozen sections): 1:20 using acetone-fixed sections western blot: 1:20-1:50 |
| 同位素/亚型 | IgG1 |
| UniProt登记号 | O15438 |
| 运输 | dry ice |
| 储存温度 | −20℃ |
| Gene Information | human ... ABCC3(8714) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
