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Monoclonal Anti-COX I antibody produced in mouse

品牌
Sigma-Aldrich
货号
C9229
规格纯度
clone AS70, purified immunoglobulin, buffered aqueous solution
参考价格
4330.86 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

免疫原

recombinant full length human COX I, 599 amino acids.

应用

Monoclonal Anti-COX I antibody produced in mouse is suitable for ELISA and western blotting. It was used to detect mitochondrial cytochrome c oxidase protein markerin homogenate and lipid droplet fractions isolated from L-cells by western blot analysis.

生化/生理作用

COX-I, an isoform of COX enzyme with 599 amino acid residues, catalyzes the conversion of arachinodate to prostaglandin H2. It is expressed mainly in the gut for the production of prostaglandins, which inhibit gastric secretion. It is involved in the regulation of homeostatic functions throughout the body, such as vascular hemostasis, renal blood flow, and maintenance of glomerular function. It is a target of NSAID (non-steroidal anti-inflammatory drugs) such as aspirin. COX-I can be induced by IL-β and other cytokines in monocytes, macrophages, and other cells as part of the inflammatory response.

外形

Solution in phosphate buffered saline, pH 7.4, containing 0.08% sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

MDL编号MFCD00217772
NACRESNA.41

产品性质

质量水平200
生物来源mouse
偶联物unconjugated
抗体形式purified immunoglobulin
antibody product typeprimary antibodies
克隆AS70, monoclonal
形式buffered aqueous solution
species reactivityhuman
浓度1 mg/mL
technique(s)indirect ELISA: suitable
western blot: suitable
同位素/亚型IgG1
UniProt登记号P23219
运输dry ice
储存温度−20℃
Gene Informationhuman ... PTGS1(5742)

Sigma-Aldrich

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