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Poly(lactide-co-glycolide)-b-poly(ethylene glycol)-b-poly(lactide-co-glycolide)

品牌
Sigma-Aldrich
货号
909076
规格纯度
average Mn (1,700-1,500-1,700), lactide:glycolide (95:5)
参考价格
3825.21 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

应用

PLGA-PEG-PLGA is an amphiphilic triblock copolymer which can self-assemble into micelles in aqueous medium due to the hydrophobic interactions present in the hydrophobic segments. The PEG segment imparts hydrophilicity and improves the biocompatibility of the copolymer. The PLGA segment forms a hydrophobic core and can solubilize hydrophobic drugs. These copolymers are widely used as nanocarriers for the sustained release of drugs. Also this polymer exhibits thermogelation behavior. When applied in biomedical applications, the temperature responsive nature of the copolymer can be tuned to induce an in situ gelation at physiological temperature to provide controlled drug release. These materials have been explored for biomedical applications as temperature-responsive biodegradable systems for drug delivery, tissue engineering and wound healing.

基本信息

线性分子式H((C3H4O2)x(C2H2O2)y)m((C2H4O)z)nO((C3H4O2)x(C2H2O2)y)mH

产品性质

形式semisolid
投料比lactide:glycolide (95:5)
分子量PEG average Mn 1,500 (by NMR)
PLGA average Mn 3,400 (by NMR)
average Mn (1,700-1,500-1,700)
颜色 white to tan
PDI≤2.0
<1.1 (Typical PEG PDI )
储存温度−20℃

安全信息

储存分类代码10 - Combustible liquids
WGKnwg
闪点(F)Not applicable
闪点(C)Not applicable

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